By all means, show us what you've got. I like crazy. Hell, I'd even take downright insane so long as it's at least a little bit feasible.

So... basically lighter then air gases can be used to effectively decrease aircraft weight. Airplanes have alot of void space in them, and that space is filled with regular air. If we displaced it with Helium, the aircraft would, effectively, be lighter. Most planes don't have enough void space though to make this a significant source of lift.

However, If we took a shape that was larger, that might not be true.

The Spruce Goose was a giant behemoth designed using old material (wood) with a huge amount of empty space in the wings. IF it was adapted so that the empty space could be filled with LTA gas, that empty space could be put to work passively generating lift for the air craft even when not in flight.
The Spruce Goose flew because it was a flying wing. They produce greater amounts of lift then a conventional air craft, but tend to be more unstable. The Instability is reduced through less then super sonic speeds.

If a hybrid craft could achieve even a marked percentage weight reduction, like 80% reduction in weight of the vehicle, flying larger loads becomes viable, especially if the vehicle is a blimp shaped like a plane.

So... then you run into mixing airplane and blimp designs to get the best of both worlds: high lift efficiency and high speed.